Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23506473 | 1.00 | CYP51A1 (0.54) | CYP51A1PYGL | |
| SCHEMBL21702171 | 0.96 | CYP51A1 (0.52) | CYP51A1PYGL | |
| SCHEMBL23506504 | 0.96 | CYP51A1 (0.52) | CYP51A1PYGL | |
| SCHEMBL21702293 | 0.94 | CYP51A1 (0.46) | CYP51A1 | |
| SCHEMBL23506432 | 0.94 | CYP51A1 (0.46) | CYP51A1 | |
| SCHEMBL21702055 | 0.92 | CYP51A1 (0.51) | CYP51A1PYGL | |
| SCHEMBL23506529 | 0.91 | PYGL (0.53) | CYP51A1PYGL | |
| SCHEMBL21702185 | 0.91 | PYGL (0.53) | CYP51A1PYGL | |
| SCHEMBL23506345 | 0.90 | CYP51A1 (0.45) | CYP51A1 | |
| SCHEMBL21702296 | 0.90 | CYP51A1 (0.45) | CYP51A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230133600-A1 | PHARMACEUTICAL USE OF KETOAMIDE-BASED COMPOUND | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2023-05-04 | — | — | US | disclosed |
| WO-2020030143-A1 | KETOAMIDE COMPOUND AND PREPARATION METHOD, PHARMACEUTICAL COMPOSITION, AND USE THEREOF | 中国科学院上海药物研究所 | 2020-02-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230133600-A1 | PHARMACEUTICAL USE OF KETOAMIDE-BASED COMPOUND | CTSL, CTSV, CTSS | CYP51A1 33/4885PYGL 1162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.