2-Mercaptobenzothiazole

2-Mercaptobenzothiazole

SCHEMBL2170236

C.Cc1nc2cc(O)ccc2s1.Sc1nc2ccccc2s1

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.49
RAB9A P51151 6/20 0.49
NPC1 O15118 6/20 0.49
KDM4E B2RXH2 6/20 0.49
NPSR1 Q6W5P4 1/20 0.49
SMN1; SMN2 Q16637 5/20 0.44
HSD17B10 Q99714 4/20 0.44
LMNA P02545 3/20 0.43
TP53 P04637 3/20 0.43
POLB P06746 3/20 0.43
PDE10A Q9Y233 1/20 0.43
NFKB1 P19838 1/20 0.43
NFKB2 Q00653 1/20 0.43
RELA Q04206 1/20 0.43
ALDH1A1 P00352 3/20 0.42
GAA P10253 2/20 0.42
GLA P06280 1/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
HTT P42858 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3046846 0.82 CA2 (0.53) MAPTRAB9ANPC1KDM4ENPSR1
SCHEMBL30106441 0.82 SMN1; SMN2 (0.61) MAPTRAB9ANPC1KDM4ENPSR1
SCHEMBL282023 0.82 SMN1; SMN2 (0.61) MAPTRAB9ANPC1KDM4ENPSR1
2-Mercaptobenzothiazole SCHEMBL2172823 0.82 PDE10A (0.49) MAPTRAB9ANPC1KDM4ESMN1; SMN2
Methane SCHEMBL2171653 0.82 PDE10A (0.49) MAPTRAB9ANPC1KDM4ESMN1; SMN2
Hydrochloric Acid SCHEMBL31731285 0.81 SMN1; SMN2 (0.59) MAPTRAB9ANPC1KDM4ENPSR1
SCHEMBL2170238 0.80 SMN1; SMN2 (0.50) MAPTRAB9ANPC1KDM4ENPSR1
2-Mercaptobenzothiazole SCHEMBL11526465 0.77 ALDH1A1 (0.52) MAPTRAB9ANPC1KDM4ESMN1; SMN2
2-Mercaptobenzothiazole SCHEMBL1247155 0.77 ALDH1A1 (0.52) MAPTRAB9ANPC1KDM4ESMN1; SMN2
2-Mercaptobenzothiazole SCHEMBL28322995 0.76 ALDH1A1 (0.47) MAPTRAB9ANPC1KDM4ENPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2346956-A1 ACTIVATORS FOR TWO PART CYANOACRYLATE ADHESIVES Loctite (R & D) Limited (IE) 2011-07-27 EP disclosed
WO-2010046412-A1 ACTIVATORS FOR TWO PART CYANOACRYLATE ADHESIVES LOCTITE (R & D) LIMITED (IE) 2010-04-29 WO disclosed