Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 6/20 | 0.42 |
| ▸ | PPARD | Q03181 | 5/20 | 0.42 |
| ▸ | PPARA | Q07869 | 5/20 | 0.42 |
| ▸ | PHGDH | O43175 | 1/20 | 0.41 |
| ▸ | GALR3 | O60755 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21683294 | 0.76 | L3MBTL1 (0.47) | L3MBTL1PPARGPPARDPPARAPHGDH | |
| SCHEMBL21702468 | 0.73 | HDAC4 (0.46) | L3MBTL1PPARGPPARDPPARAPHGDH | |
| SCHEMBL20108994 | 0.72 | L3MBTL1 (0.49) | L3MBTL1PPARGPPARDPPARAPHGDH | |
| SCHEMBL6378084 | 0.65 | L3MBTL1 (0.47) | L3MBTL1PPARGPPARDPPARAPHGDH | |
| SCHEMBL2215247 | 0.63 | GRN (0.49) | PHGDHACKR3 | |
| SCHEMBL27788500 | 0.62 | ACKR3 (0.37) | ACKR3 | |
| SCHEMBL15651678 | 0.62 | SMYD3 (0.38) | L3MBTL1PHGDHACKR3 | |
| SCHEMBL19463739 | 0.62 | HDAC4 (0.59) | — | |
| SCHEMBL9195354 | 0.61 | L3MBTL1 (0.64) | L3MBTL1PPARGPPARDPPARAPHGDH | |
| SCHEMBL24860614 | 0.60 | POLB (0.43) | LMNATP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020033413-A2 | MODULATORS OF RAS GTPASE | TOSK, INC. (US) | 2020-02-13 | — | — | WO | disclosed |