Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 4/20 | 0.49 |
| ▸ | PPARD | Q03181 | 4/20 | 0.49 |
| ▸ | PPARA | Q07869 | 4/20 | 0.49 |
| ▸ | WDR5 | P61964 | 2/20 | 0.46 |
| ▸ | PHGDH | O43175 | 1/20 | 0.42 |
| ▸ | GALR3 | O60755 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 3/20 | 0.40 |
| ▸ | CNR2 | P34972 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18112681 | 0.80 | GALR3 (0.64) | L3MBTL1PPARGPPARDPPARAWDR5 | |
| SCHEMBL21683294 | 0.76 | L3MBTL1 (0.47) | L3MBTL1PPARGPPARDPPARAPHGDH | |
| SCHEMBL21702505 | 0.72 | L3MBTL1 (0.43) | L3MBTL1PPARGPPARDPPARAPHGDH | |
| SCHEMBL21702468 | 0.72 | HDAC4 (0.46) | L3MBTL1PPARGPPARDPPARAPHGDH | |
| SCHEMBL18251688 | 0.70 | ERCC1 (0.60) | WDR5SMN1; SMN2HPGD | |
| SCHEMBL27788500 | 0.70 | ACKR3 (0.37) | HPGD | |
| SCHEMBL18124522 | 0.69 | MEN1 (0.48) | L3MBTL1PPARGPPARDPPARAPHGDH | |
| SCHEMBL10925245 | 0.68 | TSHR (0.54) | WDR5RAB9ASMN1; SMN2KMT2AHPGD | |
| SCHEMBL2215247 | 0.68 | GRN (0.49) | PHGDHHPGD | |
| SCHEMBL1150723 | 0.68 | WDR5 (0.46) | L3MBTL1WDR5HPGDCNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180118679-A1 | N-Methyl Pyrazoles | Prosetta Antiviral ,Inc. | 2018-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180118679-A1 | N-Methyl Pyrazoles | ZC3HAV1, MAVS, NNMT | L3MBTL1 385/4885PPARG 2055/4885PPARD 1098/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.