Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | PLK1 | P53350 | 1/20 | 0.48 |
| ▸ | DRD5 | P21918 | 2/20 | 0.46 |
| ▸ | MMP13 | P45452 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP10 | P09238 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | PRKACA | P17612 | 1/20 | 0.43 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.43 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21702522 | 0.83 | L3MBTL1 (0.52) | L3MBTL1PLK1MAPTPOLBKMT2A | |
| SCHEMBL21683299 | 0.78 | PLK1 (0.58) | PLK1MAPTPOLBKMT2AHDAC1 | |
| SCHEMBL23780470 | 0.78 | HDAC6 (0.62) | PLK1MMP13PRKACAHDAC1HDAC6 | |
| SCHEMBL21683294 | 0.78 | L3MBTL1 (0.47) | L3MBTL1PLK1MAPTPOLBKMT2A | |
| SCHEMBL23291895 | 0.77 | PLK1 (0.57) | PLK1MAPTPOLBKMT2AHDAC1 | |
| SCHEMBL23791596 | 0.75 | PLK1 (0.55) | PLK1MAPTPOLBKMT2AHDAC1 | |
| SCHEMBL23292063 | 0.74 | HDAC1 (0.48) | PLK1MAPTPOLBKMT2AHDAC1 | |
| SCHEMBL29064129 | 0.73 | PPARG (0.57) | L3MBTL1BAZ2BKMT2AHDAC1HDAC6 | |
| SCHEMBL23780436 | 0.72 | SMN1; SMN2 (0.48) | PLK1MAPTPOLBKMT2AHDAC1 | |
| SCHEMBL30172405 | 0.72 | SMN1; SMN2 (0.48) | PLK1MAPTPOLBKMT2AHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020033413-A2 | MODULATORS OF RAS GTPASE | TOSK, INC. (US) | 2020-02-13 | — | — | WO | disclosed |