SCHEMBL2171870

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2169004	0.91	P2RX7 (0.40)	TSHRALOX15P2RX7MAPTHSD17B10
	SCHEMBL13368764	0.90	HCRTR1 (0.40)	TP53TSHRLMNAALOX15P2RX7
	SCHEMBL2170533	0.90	CXCR3 (0.38)	P2RX7KDM4EALDH1A1HSD11B1HSD11B2
	SCHEMBL2170032	0.89	HSD11B1 (0.33)	TP53TSHRLMNAALOX15P2RX7
	SCHEMBL2170385	0.86	P2RX7 (0.39)	TP53P2RX7
	SCHEMBL2169179	0.83	KMT2A (0.39)	P2RX7ALDH1A1MAPTHSD17B10
	SCHEMBL2170075	0.83	CHRNA7 (0.41)	TSHRALDH1A1HSD11B1
	SCHEMBL2169753	0.82	P2RX7 (0.42)	P2RX7KDM4EALDH1A1HSD11B1
	SCHEMBL2169563	0.82	P2RX7 (0.40)	TP53P2RX7ALDH1A1HSD11B1SMN1; SMN2
	SCHEMBL2169689	0.81	P2RX7 (0.35)	TSHRALOX15P2RX7HSD11B1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.