SCHEMBL21705259

SCHEMBL21705259

O=C(OCCN1CCOCC1)c1ccccc1I

nearest known ligand 0.67

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.67
ATM Q13315 1/20 0.58
KMT2A Q03164 3/20 0.57
LMNA P02545 2/20 0.57
GAA P10253 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.54
HPGD P15428 1/20 0.52
BCHE P06276 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
MEN1 O00255 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP3A4 P08684 1/20 0.50
CYP2D6 P10635 1/20 0.50
CYP2C9 P11712 1/20 0.50
PKM P14618 1/20 0.50
CYP2C19 P33261 1/20 0.50
PRCP P42785 1/20 0.50
TMEM97 Q5BJF2 1/20 0.50
SIGMAR1 Q99720 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21705257 0.86 KMT2A (0.69) ALDH1A1KMT2ALMNAGAAHPGD
SCHEMBL11338527 0.85 ALDH1A1 (0.69) ALDH1A1ATMKMT2ALMNAGAA
SCHEMBL21705264 0.84 HPGD (0.55) ALDH1A1KMT2AHPGDCYP1A2CYP2D6
SCHEMBL31006164 0.84 ALDH1A1 (0.67) ALDH1A1ATMKMT2ALMNAGAA
SCHEMBL21705720 0.84 KMT2A (0.52) ALDH1A1KMT2ALMNAHPGDBCHE
SCHEMBL21705697 0.83 KMT2A (0.51) ALDH1A1KMT2AL3MBTL1HPGDMEN1
SCHEMBL11622167 0.82 ALDH1A1 (0.64) ALDH1A1ATMKMT2ALMNAGAA
SCHEMBL24177747 0.82 ALDH1A1 (0.97) ALDH1A1ATMKMT2ALMNAGAA
SCHEMBL501899 0.82 CNR1 (0.65) ALDH1A1ATMKMT2ALMNAGAA
SCHEMBL501720 0.80 ATM (0.76) ALDH1A1ATMKMT2ALMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11835859-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-12-05 US disclosed
US-11774853-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-10-03 US disclosed
US-11774853-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-10-03 US disclosed
US-20230129578-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-04-27 US disclosed
US-20230129578-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-04-27 US disclosed
US-11187980-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-11-30 US disclosed
US-20200192222-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-06-18 US disclosed
US-20200073237-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-03-05 US disclosed
US-20200050105-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-02-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200050105-A1 RESIST COMPOSITION AND PATTERNING PROCESS HNRNPU, HNRNPR, ZFR ALDH1A1 4859/4885ATM 3719/4885KMT2A 913/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.