SCHEMBL21705264

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21705257	0.86	KMT2A (0.69)	HPGDKMT2AALDH1A1CYP1A2CYP2D6
	SCHEMBL21705720	0.84	KMT2A (0.52)	HPGDKMT2AALDH1A1CYP1A2CYP2D6
	SCHEMBL21705259	0.84	ALDH1A1 (0.67)	HPGDKMT2AALDH1A1CYP1A2CYP2D6
	SCHEMBL21705697	0.83	KMT2A (0.51)	HPGDKMT2AALDH1A1CYP1A2CYP2D6
	SCHEMBL18891134	0.80	MEN1 (0.55)	HPGDKMT2AALDH1A1SIGMAR1KDM4E
	SCHEMBL21783770	0.79	HPGD (0.41)	HPGDKMT2AALDH1A1CYP1A2CYP2D6
	SCHEMBL15047632	0.78	KMT2A (0.63)	HPGDKMT2AALDH1A1CYP2D6KDM4E
	SCHEMBL21705614	0.78	HPGD (0.41)	HPGDKMT2AALDH1A1CYP1A2CYP2D6
	SCHEMBL21705263	0.78	KMT2A (0.56)	HPGDKMT2AALDH1A1CYP1A2CYP2D6
	SCHEMBL21705258	0.76	NPSR1 (0.52)	HPGDKMT2AALDH1A1SIGMAR1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.