SCHEMBL21705697

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12551126	0.85	KMT2A (0.52)	KMT2AHPGDALDH1A1CYP1A2CYP2D6
	SCHEMBL21705257	0.85	KMT2A (0.69)	KMT2AHPGDALDH1A1CYP1A2CYP2D6
	SCHEMBL12550836	0.84	KMT2A (0.51)	KMT2AHPGDALDH1A1CYP1A2CYP2D6
	SCHEMBL21705264	0.83	HPGD (0.55)	KMT2AHPGDALDH1A1CYP1A2CYP2D6
	SCHEMBL21705259	0.83	ALDH1A1 (0.67)	KMT2AHPGDALDH1A1CYP1A2CYP2D6
	SCHEMBL21705720	0.83	KMT2A (0.52)	KMT2AHPGDALDH1A1CYP1A2CYP2D6
	SCHEMBL12550718	0.82	HRH3 (0.67)	KMT2AHPGDALDH1A1CYP1A2CYP2D6
	SCHEMBL12550837	0.82	DRD2 (0.52)	KMT2AHPGDALDH1A1CYP1A2CYP2D6
	SCHEMBL12550739	0.82	CHRNB2 (0.52)	KMT2AHPGDALDH1A1CYP1A2CYP2D6
	SCHEMBL12550691	0.81	HRH3 (0.56)	KMT2AALDH1A1HRH3MEN1DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.