SCHEMBL21707000

SCHEMBL21707000

Fc1ccc(-n2c3ccccc3c3c4cccc(-c5ccc(N(c6ccccc6)c6ccc(-c7ccccc7)cc6)cc5)c4n(-c4ccc(F)cc4)c32)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR3C1 P04150 1/20 0.35
CDK1 P06493 1/20 0.33
CDK4 P11802 1/20 0.33
CCNB1 P14635 1/20 0.33
CCNA2 P20248 1/20 0.33
CCND1 P24385 1/20 0.33
CDK2 P24941 1/20 0.33
CDK7 P50613 1/20 0.33
CCNH P51946 1/20 0.33
NPSR1 Q6W5P4 1/20 0.32
RXFP1 Q9HBX9 1/20 0.32
MAPK14 Q16539 1/20 0.32
MAPT P10636 1/20 0.32
GRIA1 P42261 1/20 0.32
CACNG8 Q8WXS5 1/20 0.32
CACNG2 Q9Y698 1/20 0.32
HKDC1 Q2TB90 3/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
CXCR3 P49682 1/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21707148 0.92 L3MBTL1 (0.36) MAPK14MAPTALDH1A1KMT2A
SCHEMBL21707088 0.89 CDK1 (0.32) NR3C1CDK1CDK4CCNB1CCNA2
SCHEMBL21707005 0.88 NR3C1 (0.33) NR3C1NPSR1RXFP1MAPK14GRIA1
SCHEMBL21706856 0.84 NR3C1 (0.38) NR3C1NPSR1RXFP1MAPK14GRIA1
SCHEMBL21706815 0.84 NR3C1 (0.35) NR3C1NPSR1RXFP1MAPK14GRIA1
SCHEMBL21706996 0.84 NR3C1 (0.40) NR3C1NPSR1RXFP1MAPK14GRIA1
SCHEMBL21706816 0.84 NR3C1 (0.38) NR3C1NPSR1RXFP1MAPK14GRIA1
SCHEMBL17722259 0.81 L3MBTL1 (0.41) MAPK14MAPTALDH1A1KMT2A
SCHEMBL17722300 0.81 L3MBTL1 (0.41) MAPK14MAPTALDH1A1KMT2A
SCHEMBL21707003 0.81 NR3C1 (0.32) NR3C1NPSR1RXFP1MAPK14GRIA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200052223-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2020-02-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200052223-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNE2 NR3C1 714/4885CDK1 15/4885CDK4 52/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.