Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | TSHR | P16473 | 3/20 | 0.31 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.31 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.31 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.31 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.31 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.31 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.31 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.31 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.31 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.31 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.31 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.31 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.31 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.31 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.31 |
| ▸ | PSMB3 | P49720 | 1/20 | 0.31 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4957416 | 0.71 | AAK1 (0.38) | ALDH1A1TSHRPSMB11PSMA7PSMB1 | |
| SCHEMBL4867348 | 0.70 | ALDH1A1 (0.46) | ALDH1A1TSHRSMN1; SMN2MAPTPOLB | |
| SCHEMBL29215007 | 0.70 | TSHR (0.60) | ALDH1A1TSHRSMN1; SMN2KDM4ETP53 | |
| SCHEMBL4866526 | 0.70 | LMNA (0.36) | HTTALDH1A1KDM4EGAAPOLB | |
| SCHEMBL2163020 | 0.69 | GPR88 (0.44) | ALDH1A1SMN1; SMN2KDM4EHPGDMAPT | |
| SCHEMBL4954828 | 0.68 | HTR1A (0.38) | GAAMAPT | |
| SCHEMBL4866147 | 0.68 | SLC6A2 (0.38) | — | |
| SCHEMBL12347521 | 0.68 | ALDH1A1 (0.44) | HTTALDH1A1TSHRSMN1; SMN2KDM4E | |
| SCHEMBL7269906 | 0.67 | SLC7A5 (0.34) | — | |
| SCHEMBL13129179 | 0.66 | SLC6A2 (0.43) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7973037-B2 | Cathepsin cysteine protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2011-07-05 | — | — | US | disclosed |