Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2172805 | 0.86 | TTR (0.31) | — | |
| SCHEMBL12336849 | 0.81 | L3MBTL1 (0.38) | GRM2L3MBTL1TDP1MAPK1 | |
| SCHEMBL2171989 | 0.78 | GAA (0.44) | MAPK1 | |
| SCHEMBL2170715 | 0.78 | MAPK1 (0.44) | GRM2L3MBTL1TDP1CXCR2MAPK1 | |
| SCHEMBL12336850 | 0.76 | HSP90AB1 (0.34) | GRM2 | |
| SCHEMBL3266419 | 0.64 | MAPK1 (0.40) | GRM2L3MBTL1TDP1MAPK1 | |
| SCHEMBL2315369 | 0.63 | MAPK1 (0.41) | TDP1MAPK1 | |
| SCHEMBL3238214 | 0.62 | MAPK1 (0.39) | GRM2MAPK1 | |
| SCHEMBL3237661 | 0.62 | MAPK1 (0.40) | GRM2MAPK1 | |
| SCHEMBL28020713 | 0.62 | GRM2 (0.52) | GRM2L3MBTL1TDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110190122-A1 | Triazole and Imidazole Compounds, Use Thereof and Agents Containing Them | BASF SE (DE) | 2011-08-04 | — | — | US | disclosed |
| EP-2346839-A1 | TRIAZOLE AND IMIDAZOLE COMPOUNDS, USE THEREOF AND AGENTS CONTAINING THEM | BASF SE (DE) | 2011-07-27 | — | — | EP | disclosed |
| WO-2010040717-A1 | TRIAZOLE AND IMIDAZOLE COMPOUNDS, USE THEREOF AND AGENTS CONTAINING THEM | BASF SE (DE) | 2010-04-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110190122-A1 | Triazole and Imidazole Compounds, Use Thereof and Agents Containing Them | ABAT, OAT, TYR | GRM2 4587/4885L3MBTL1 3164/4885TDP1 1292/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.