Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | MPO | P05164 | 2/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | BACE1 | P56817 | 2/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2169612 | 0.88 | HSD11B1 (0.34) | MEN1KMT2AEPHX2TSHRHSD11B1 | |
| SCHEMBL2170813 | 0.86 | PTGS1 (0.38) | MEN1KMT2ATSHRACHEHSD11B1 | |
| SCHEMBL2168659 | 0.85 | P2RX7 (0.34) | KDM4ETSHRHSD11B1ALDH1A1CA12 | |
| SCHEMBL2168703 | 0.85 | P2RX7 (0.40) | MEN1KMT2AKDM4ECYP2D6TSHR | |
| SCHEMBL2168978 | 0.85 | EPHX2 (0.40) | MEN1KMT2AEPHX2KDM4ECYP2D6 | |
| SCHEMBL2169125 | 0.85 | HSD11B1 (0.33) | EPHX2HSD11B1SIRT1 | |
| SCHEMBL2169766 | 0.83 | GRM2 (0.35) | BRD4HSD11B1TACR1 | |
| SCHEMBL2169964 | 0.83 | USP2 (0.43) | MEN1KMT2AKDM4ECYP2D6TSHR | |
| SCHEMBL2170753 | 0.83 | ACHE (0.40) | CYP2D6TSHRACHEALDH1A1CA12 | |
| SCHEMBL2168576 | 0.82 | NPSR1 (0.41) | MEN1KMT2AKDM4ECYP2D6HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2348019-A1 | 1,2-DIAZETIDIN-3-ONE DERIVATIVE AND PHARMACEUTICAL AGENT COMPRISING SAME | Kowa Company, Ltd. (JP) | 2011-07-27 | — | — | EP | disclosed |