SCHEMBL2169964

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2169612	0.85	HSD11B1 (0.34)	USP2KMT2AMEN1TSHR
	SCHEMBL2170813	0.84	PTGS1 (0.38)	KMT2AMEN1TSHRSMN1; SMN2POLB
	SCHEMBL2169125	0.83	HSD11B1 (0.33)	HTR2A
	SCHEMBL2168978	0.83	EPHX2 (0.40)	KMT2AMEN1CYP2D6NPC1TSHR
	SCHEMBL2168659	0.83	P2RX7 (0.34)	TSHRKDM4EALDH1A1
	SCHEMBL2170857	0.83	MEN1 (0.40)	USP2KMT2AMEN1CYP2D6TSHR
	SCHEMBL2168703	0.83	P2RX7 (0.40)	KMT2AMEN1CYP2D6NPC1TSHR
	SCHEMBL2168347	0.81	HSD17B10 (0.35)	HSD17B10CHRM2
	SCHEMBL2169766	0.81	GRM2 (0.35)	—
	SCHEMBL2170753	0.81	ACHE (0.40)	HSD17B10CYP2D6TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.