Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.32 |
| ▸ | PTGFR | P43088 | 3/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21708642 | 0.94 | TAS1R3 (0.34) | TAS1R3TAS1R1L3MBTL1PTGFRKIF11 | |
| SCHEMBL21708704 | 0.87 | TAS1R3 (0.33) | TAS1R3TAS1R1L3MBTL1KIF11CTSK | |
| SCHEMBL21708706 | 0.82 | L3MBTL1 (0.32) | TAS1R3TAS1R1L3MBTL1CTSKALDH1A1 | |
| SCHEMBL21708756 | 0.80 | PTGFR (0.33) | L3MBTL1PTGFR | |
| SCHEMBL21656375 | 0.79 | PTGFR (0.36) | L3MBTL1PTGFRKIF11LMNAMEN1 | |
| SCHEMBL21708740 | 0.77 | L3MBTL1 (0.32) | TAS1R3TAS1R1L3MBTL1ALDH1A1 | |
| SCHEMBL21632132 | 0.76 | PTGFR (0.46) | L3MBTL1PTGFRKIF11MEN1KMT2A | |
| SCHEMBL21708652 | 0.75 | TAS1R3 (0.34) | TAS1R3TAS1R1KIF11 | |
| SCHEMBL21708716 | 0.75 | L3MBTL1 (0.36) | TAS1R3TAS1R1L3MBTL1PTGFRGAA | |
| SCHEMBL21632147 | 0.71 | PTGFR (0.44) | L3MBTL1PTGFRKIF11ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609869-A1 | SUBSTITUTED N-ARYLETHYL-2-ARYLQUINOLINE-4-CARBOXAMIDES AND USE THEREOF | Bayer Aktiengesellschaft (DE) | 2020-02-19 | — | — | EP | disclosed |