Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21708740 | 0.94 | L3MBTL1 (0.32) | L3MBTL1TAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL21708795 | 0.87 | TAS1R3 (0.33) | TAS1R3TAS1R1CTSKALDH1A1 | |
| SCHEMBL21708644 | 0.82 | TAS1R3 (0.33) | L3MBTL1TAS1R3TAS1R1CTSKALDH1A1 | |
| SCHEMBL21708659 | 0.80 | SLC6A3 (0.32) | L3MBTL1 | |
| SCHEMBL21656182 | 0.80 | CTSS (0.32) | CTSKALDH1A1 | |
| SCHEMBL21708642 | 0.78 | TAS1R3 (0.34) | L3MBTL1TAS1R3TAS1R1CTSKALDH1A1 | |
| SCHEMBL21631928 | 0.77 | PTGFR (0.39) | ALDH1A1 | |
| SCHEMBL21708682 | 0.75 | CCR1 (0.39) | L3MBTL1TAS1R3TAS1R1ALDH1A1HPGD | |
| SCHEMBL21708670 | 0.74 | MEN1 (0.36) | L3MBTL1TAS1R3TAS1R1CTSKALDH1A1 | |
| SCHEMBL21656111 | 0.73 | CTSS (0.33) | CTSKALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609869-A1 | SUBSTITUTED N-ARYLETHYL-2-ARYLQUINOLINE-4-CARBOXAMIDES AND USE THEREOF | Bayer Aktiengesellschaft (DE) | 2020-02-19 | — | — | EP | disclosed |