Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 2/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21708722 | 0.90 | SMN1; SMN2 (0.48) | SMN1; SMN2GAAMEN1KMT2AALDH1A1 | |
| SCHEMBL21708794 | 0.81 | GAA (0.38) | SMN1; SMN2GAAMEN1KMT2AALDH1A1 | |
| SCHEMBL21708707 | 0.79 | CCR1 (0.36) | MEN1KMT2AALDH1A1CCR1KDM4E | |
| SCHEMBL21708548 | 0.79 | MEN1 (0.35) | SMN1; SMN2GAAMEN1KMT2AALDH1A1 | |
| SCHEMBL21656110 | 0.79 | SMN1; SMN2 (0.48) | SMN1; SMN2GAAMEN1KMT2AALDH1A1 | |
| SCHEMBL21708512 | 0.78 | CCR1 (0.36) | SMN1; SMN2GAAMEN1KMT2AALDH1A1 | |
| SCHEMBL21708544 | 0.78 | POLB (0.38) | MEN1KMT2ATSHRLMNAHPGD | |
| SCHEMBL21708545 | 0.78 | KMT2A (0.33) | KMT2A | |
| SCHEMBL21708518 | 0.77 | TAS1R3 (0.32) | MEN1KMT2AHSD17B10 | |
| SCHEMBL21632100 | 0.76 | SMN1; SMN2 (0.49) | SMN1; SMN2GAAMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609869-A1 | SUBSTITUTED N-ARYLETHYL-2-ARYLQUINOLINE-4-CARBOXAMIDES AND USE THEREOF | Bayer Aktiengesellschaft (DE) | 2020-02-19 | — | — | EP | disclosed |