Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.30 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.30 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
| ▸ | F2R | P25116 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21708723 | 0.92 | RIPK1 (0.36) | KMT2A | |
| SCHEMBL21708524 | 0.90 | CTSS (0.32) | F2R | |
| SCHEMBL21708609 | 0.90 | KMT2A (0.34) | KMT2AADRB1 | |
| SCHEMBL21708561 | 0.87 | CCR1 (0.30) | KMT2A | |
| SCHEMBL21708707 | 0.87 | CCR1 (0.36) | KMT2ATAS1R3TAS1R1ADRB1ADRB2 | |
| SCHEMBL21708518 | 0.87 | TAS1R3 (0.32) | KMT2ATAS1R3TAS1R1 | |
| SCHEMBL21708678 | 0.85 | — | — | |
| SCHEMBL21708459 | 0.85 | CCR1 (0.32) | KMT2AADRB1 | |
| SCHEMBL21708563 | 0.83 | MEN1 (0.31) | KMT2A | |
| SCHEMBL21708626 | 0.81 | L3MBTL1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609870-A1 | SUBSTITUTED N-ARYLETHYL-2-AMINOQUINOLINE-4-CARBOXAMIDES AND USE THEREOF | Bayer Aktiengesellschaft (DE) | 2020-02-19 | — | — | EP | disclosed |
| EP-3609869-A1 | SUBSTITUTED N-ARYLETHYL-2-ARYLQUINOLINE-4-CARBOXAMIDES AND USE THEREOF | Bayer Aktiengesellschaft (DE) | 2020-02-19 | — | — | EP | disclosed |