Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | PDE4A | P27815 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21708665 | 0.89 | GAA (0.38) | GAASMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL21708690 | 0.81 | SMN1; SMN2 (0.47) | GAASMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL21708785 | 0.79 | ROCK2 (0.32) | GAAALDH1A1ESR1SLC6A3PTGFR | |
| SCHEMBL21708658 | 0.79 | TAS1R3 (0.34) | GAAMEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL21656127 | 0.78 | CYP2C19 (0.41) | GAASMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL21510400 | 0.78 | TSHR (0.51) | GAASMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL21708590 | 0.78 | L3MBTL1 (0.41) | MEN1KMT2ATSHRKDM4ETDP1 | |
| SCHEMBL21708509 | 0.78 | NISCH (0.36) | GAAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL21708613 | 0.77 | TAS1R3 (0.33) | PTGFR | |
| SCHEMBL21632347 | 0.76 | GABBR2 (0.44) | SMN1; SMN2ALDH1A1CYP1A2TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609869-A1 | SUBSTITUTED N-ARYLETHYL-2-ARYLQUINOLINE-4-CARBOXAMIDES AND USE THEREOF | Bayer Aktiengesellschaft (DE) | 2020-02-19 | — | — | EP | disclosed |