Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | BLM | P54132 | 2/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.57 |
| ▸ | ALPG | P10696 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.48 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21708898 | 0.96 | MAPT (0.56) | MAPTHSD17B10ALDH1A1HIF1AKDM4E | |
| SCHEMBL109163 | 0.76 | MAPT (0.74) | MAPTHSD17B10ALDH1A1HIF1AKDM4E | |
| SCHEMBL7105545 | 0.76 | MAPT (0.74) | MAPTHSD17B10ALDH1A1HIF1AKDM4E | |
| SCHEMBL21709273 | 0.75 | MAPT (0.59) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL6420228 | 0.75 | MAPT (0.72) | MAPTHSD17B10ALDH1A1HIF1AKDM4E | |
| SCHEMBL15924294 | 0.74 | MAPT (0.61) | MAPTHSD17B10ALDH1A1HIF1AKDM4E | |
| SCHEMBL25380895 | 0.73 | MAPT (0.70) | MAPTHSD17B10ALDH1A1HIF1AKDM4E | |
| SCHEMBL328568 | 0.73 | MAPT (1.00) | MAPTHSD17B10ALDH1A1HIF1AKDM4E | |
| SCHEMBL109158 | 0.73 | MAPT (0.73) | MAPTHSD17B10ALDH1A1HIF1AKDM4E | |
| SCHEMBL5500828 | 0.73 | MAPT (0.70) | MAPTHSD17B10ALDH1A1HIF1AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020032080-A1 | COMPOUND, SALT OF COMPOUND, NEUROMODULATION AGENT, METHOD FOR EVALUATING NEUROMODULATION AGENT, METHOD FOR PRODUCING COMPOUND, AND METHOD FOR PRODUCING SALT OF COMPOUND | 学校法人慶應義塾 | 2020-02-13 | — | — | WO | disclosed |