SCHEMBL2170896

SCHEMBL2170896

CC(C)CCOc1nc2ccccc2s1

nearest known ligand 0.57

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 6/20 0.57
PTGS2 P35354 6/20 0.57
KMT2A Q03164 2/20 0.48
MEN1 O00255 1/20 0.48
PPARG P37231 3/20 0.47
PPARA Q07869 3/20 0.47
TLR8 Q9NR97 1/20 0.47
LOXL2 Q9Y4K0 1/20 0.45
LTA4H P09960 4/20 0.43
ALDH1A1 P00352 1/20 0.42
ALOX15 P16050 1/20 0.42
TSHR P16473 1/20 0.42
CASP1 P29466 1/20 0.42
NPC1 O15118 1/20 0.42
MAPK1 P28482 1/20 0.42
RAB9A P51151 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12877013 0.84 PTGS1 (0.54) PTGS1PTGS2KMT2AMEN1PPARG
SCHEMBL10158221 0.82 PTGS1 (0.61) PTGS1PTGS2KMT2AMEN1PPARG
SCHEMBL9167195 0.81 PTGS1 (0.64) PTGS1PTGS2KMT2AMEN1PPARG
SCHEMBL10090168 0.81 PTGS1 (0.64) PTGS1PTGS2KMT2AMEN1PPARG
SCHEMBL28282484 0.79 PTGS1 (0.58) PTGS1PTGS2KMT2AMEN1PPARG
SCHEMBL6101474 0.79 PTGS1 (0.66) PTGS1PTGS2KMT2AMEN1PPARG
SCHEMBL10729452 0.79 PTGS1 (0.61) PTGS1PTGS2KMT2AMEN1PPARG
SCHEMBL14467536 0.79 PTGS1 (0.61) PTGS1PTGS2KMT2AMEN1PPARG
SCHEMBL72049 0.79 PTGS1 (0.61) PTGS1PTGS2KMT2AMEN1PPARG
SCHEMBL10090420 0.79 PTGS1 (0.61) PTGS1PTGS2KMT2AMEN1PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4441112-A1 METHOD OF UNDERWATER BONDING Henkel AG & Co. KGaA (DE) 2024-10-09 EP claimed
US-20240318052-A1 METHOD OF UNDERWATER BONDING HENKEL AG & CO KGAA (DE) 2024-09-26 US claimed
CN-118355041-A Method for underwater bonding 汉高股份有限及两合公司 2024-07-16 CN claimed
WO-2023099777-A1 METHOD OF UNDERWATER BONDING Henkel IP & Holding GmbH (DE) 2023-06-08 WO claimed
EP-3464446-B1 TWO-PART CYANOACRYLATE CURABLE ADHESIVE SYSTEM Henkel IP & Holding GmbH (DE) 2021-06-23 EP claimed
CN-109476874-B Two-part cyanoacrylate curable adhesive systems 汉高知识产权控股有限责任公司 2021-04-16 CN claimed
EP-3464446-A1 TWO-PART CYANOACRYLATE CURABLE ADHESIVE SYSTEM Henkel IP & Holding GmbH (DE) 2019-04-10 EP claimed
US-10100235-B2 Two-part cyanoacrylate curable adhesive system Henkel IP & Holding GmbH (DE) 2018-10-16 US claimed
WO-2017202698-A1 TWO-PART CYANOACRYLATE CURABLE ADHESIVE SYSTEM Henkel IP & Holding GmbH (DE) 2017-11-30 WO claimed
US-20170335151-A1 TWO-PART CYANOACRYLATE CURABLE ADHESIVE SYSTEM HENKEL AG & CO. KGAA (DE) 2017-11-23 US claimed
EP-2346956-A1 ACTIVATORS FOR TWO PART CYANOACRYLATE ADHESIVES Loctite (R & D) Limited (IE) 2011-07-27 EP claimed
WO-2010046412-A1 ACTIVATORS FOR TWO PART CYANOACRYLATE ADHESIVES LOCTITE (R & D) LIMITED (IE) 2010-04-29 WO claimed
EP-4441112-A1 METHOD OF UNDERWATER BONDING Henkel AG & Co. KGaA (DE) 2024-10-09 EP disclosed
US-20240318052-A1 METHOD OF UNDERWATER BONDING HENKEL AG & CO KGAA (DE) 2024-09-26 US disclosed
CN-118355041-A Method for underwater bonding 汉高股份有限及两合公司 2024-07-16 CN disclosed
WO-2023099777-A1 METHOD OF UNDERWATER BONDING Henkel IP & Holding GmbH (DE) 2023-06-08 WO disclosed
US-7514440-B2 Fused pyrrolocarbazoles CEPHALON, INC. (US) 2009-04-07 US disclosed
US-7514440-B2 Fused pyrrolocarbazoles CEPHALON, INC. (US) 2009-04-07 US disclosed
US-20070203135-A1 Novel Fused Pyrrolocarbazoles CEPHALON, INC. (US) 2007-08-30 US disclosed
US-20070203135-A1 Novel Fused Pyrrolocarbazoles CEPHALON, INC. (US) 2007-08-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070203135-A1 Novel Fused Pyrrolocarbazoles PC, PYCR1, CYP11B2 PTGS1 454/4885PTGS2 311/4885KMT2A 4331/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.