SCHEMBL21709094

SCHEMBL21709094

C#CCn1cc(CCN)c2c(C#C)c(O)ccc21

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.32
HTR2A P28223 2/20 0.31
HTR2C P28335 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21709087 0.73 EGFR (0.42) TAAR1HTR2AHTR2C
Hydrochloric Acid SCHEMBL21693918 0.72 EGFR (0.43) TAAR1HTR2AHTR2C
SCHEMBL21709100 0.71 MEN1 (0.33) HTR2A
SCHEMBL8758848 0.69 HTR2A (0.55) HTR2A
SCHEMBL21709092 0.67 HTR2C (0.57) TAAR1HTR2AHTR2C
SCHEMBL21708941 0.64 ADRB2 (0.46)
SCHEMBL21709095 0.63 HTR1A (0.31) TAAR1HTR2AHTR2C
SCHEMBL30681597 0.62 HTR2C (0.70) TAAR1HTR2AHTR2C
SCHEMBL14801810 0.60 CHEK1 (0.37) HTR2A
SCHEMBL30681642 0.60 HTR2C (0.61) TAAR1HTR2AHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020032080-A1 COMPOUND, SALT OF COMPOUND, NEUROMODULATION AGENT, METHOD FOR EVALUATING NEUROMODULATION AGENT, METHOD FOR PRODUCING COMPOUND, AND METHOD FOR PRODUCING SALT OF COMPOUND 学校法人慶應義塾 2020-02-13 WO disclosed