Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 2/20 | 0.49 |
| ▸ | OGG1 | O15527 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | FNTA | P49354 | 1/20 | 0.46 |
| ▸ | FNTB | P49356 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | TNKS | O95271 | 1/20 | 0.44 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.44 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.44 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.44 |
| ▸ | ACACB | O00763 | 2/20 | 0.44 |
| ▸ | ACACA | Q13085 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2171656 | 0.85 | EPHX1 (0.49) | FNTAFNTBKMT2APARP15PARP14 | |
| SCHEMBL2173030 | 0.83 | PARP10 (0.55) | PTGS1ALOX5KMT2AMEN1CYP2D6 | |
| SCHEMBL5018845 | 0.81 | MAPT (0.47) | OGG1PTGS1FNTAFNTBMGLL | |
| SCHEMBL7040469 | 0.79 | PTGS1 (0.77) | PTGS1ALOX5KMT2AMEN1CYP2D6 | |
| SCHEMBL7032448 | 0.79 | PTGS1 (0.77) | PTGS1ALOX5KMT2AMEN1CYP2D6 | |
| SCHEMBL2055566 | 0.78 | TRPM8 (0.52) | OGG1APP | |
| SCHEMBL2172240 | 0.77 | EPHX1 (0.50) | ALOX5FNTAFNTBKMT2APARP15 | |
| SCHEMBL2169718 | 0.77 | PARP10 (0.58) | PTGS1ALOX5KMT2AMEN1PARP10 | |
| SCHEMBL10715309 | 0.76 | MAPT (0.54) | KMT2AMEN1NAAA | |
| SCHEMBL5804600 | 0.75 | OGG1 (0.69) | OGG1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346821-A1 | SPHINGOSINE-1-PHOSPHATE RECEPTOR ANTAGONISTS | Exelixis, Inc. (US) | 2011-07-27 | — | — | EP | disclosed |