SCHEMBL21709148

SCHEMBL21709148

C#CCNCCc1cc(O)c(O)cc1C#C

nearest known ligand 0.46

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ACHE P22303 3/20 0.35
MAOA P21397 3/20 0.32
MAOB P27338 1/20 0.32
MPO P05164 1/20 0.32
SAT1 P21673 1/20 0.32
HTR2A P28223 1/20 0.31
HTR2C P28335 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21708864 0.83 HTR2A (0.33) ACHEMAOAHTR2AHTR2C
SCHEMBL21709263 0.78 HTR2A (0.42) ACHEHTR2AHTR2C
SCHEMBL21709190 0.77 HMGCR (0.40)
SCHEMBL21708876 0.75 ACHE (0.34) ACHEMAOAMAOBHTR2AHTR2C
SCHEMBL21708917 0.74 ACHE (0.39) ACHEMAOASAT1
SCHEMBL21709146 0.74 TSHR (0.36)
SCHEMBL21709102 0.73 KDM4E (0.42) MPOHTR2AHTR2C
SCHEMBL21708855 0.71 MAPT (0.61) ACHEHTR2A
Hydrochloric Acid SCHEMBL21693933 0.70 KDM4E (0.62) ACHEHTR2A
SCHEMBL21709150 0.70 CA12 (0.39) MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020032080-A1 COMPOUND, SALT OF COMPOUND, NEUROMODULATION AGENT, METHOD FOR EVALUATING NEUROMODULATION AGENT, METHOD FOR PRODUCING COMPOUND, AND METHOD FOR PRODUCING SALT OF COMPOUND 学校法人慶應義塾 2020-02-13 WO disclosed