Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 8/20 | 0.58 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.52 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.52 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | PPARD | Q03181 | 1/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.47 |
| ▸ | GNA15 | P30679 | 1/20 | 0.45 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | RXRB | P28702 | 1/20 | 0.45 |
| ▸ | RXRG | P48443 | 1/20 | 0.45 |
| ▸ | TNKS | O95271 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2171661 | 0.85 | FFAR1 (0.53) | FFAR1FFAR4KMT2APPARGSRD5A2 | |
| SCHEMBL2173032 | 0.83 | FFAR1 (0.74) | FFAR1FFAR4SRD5A2PARP10LTA4H | |
| SCHEMBL1048214 | 0.80 | MAOB (0.61) | LPAR1LPAR5MEN1ALDH1A1KMT2A | |
| SCHEMBL4426732 | 0.79 | WDR5 (0.56) | FFAR1ALDH1A1ADRB3TNKSPARP15 | |
| SCHEMBL18957609 | 0.79 | SLC5A1 (0.62) | FFAR1LPAR1LPAR5FFAR4MEN1 | |
| SCHEMBL507152 | 0.78 | ST14 (0.62) | LPAR1LPAR5MEN1ALDH1A1KMT2A | |
| SCHEMBL2473717 | 0.78 | HTR3E (0.59) | MEN1ALDH1A1KMT2A | |
| SCHEMBL30572312 | 0.78 | HTR3E (0.59) | MEN1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL31606746 | 0.77 | HTR3E (0.57) | MEN1ALDH1A1KMT2A | |
| SCHEMBL9267107 | 0.77 | LPAR1 (0.48) | FFAR1LPAR1LPAR5PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346821-A1 | SPHINGOSINE-1-PHOSPHATE RECEPTOR ANTAGONISTS | Exelixis, Inc. (US) | 2011-07-27 | — | — | EP | disclosed |