Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | SRD5A1 | P18405 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ELANE | P08246 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2170993 | 0.83 | LMNA (0.59) | SMN1; SMN2POLBLMNAALDH1A1MAPT | |
| SCHEMBL9591439 | 0.83 | SRD5A1 (0.52) | SMN1; SMN2POLBLMNASRD5A1ALDH1A1 | |
| SCHEMBL14341655 | 0.82 | SMN1; SMN2 (0.61) | SMN1; SMN2POLBLMNASRD5A1ALDH1A1 | |
| SCHEMBL4099023 | 0.82 | LMNA (0.48) | SMN1; SMN2POLBLMNAALDH1A1MAPT | |
| SCHEMBL2537515 | 0.82 | ALDH1A1 (0.71) | SMN1; SMN2POLBLMNASRD5A1ALDH1A1 | |
| SCHEMBL17471507 | 0.80 | PTGS2 (0.60) | SMN1; SMN2POLBLMNASRD5A1ALDH1A1 | |
| SCHEMBL2537514 | 0.80 | SMN1; SMN2 (0.57) | SMN1; SMN2POLBLMNASRD5A1ALDH1A1 | |
| SCHEMBL269329 | 0.80 | LMNA (0.80) | SMN1; SMN2POLBLMNAALDH1A1MAPT | |
| SCHEMBL463663 | 0.79 | LMNA (0.59) | SMN1; SMN2POLBLMNAALDH1A1MAPT | |
| SCHEMBL992564 | 0.79 | RAB9A (0.50) | SMN1; SMN2POLBLMNASRD5A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5527816-A | AGRICULTURAL USE | ROHM AND HAAS COMPANY (US) | 1996-06-18 | — | — | US | disclosed |
| EP-0529974-A1 | Fungicidal 2-aryl-2-cyano-2-(aryloxyalkyl)ethyl-1,2,4-triazoles | ROHM AND HAAS COMPANY (US) | 1993-03-03 | — | — | EP | disclosed |
| EP-0053940-B1 | POLY(ESTER-AMIDE) CAPABLE OF FORMING AN ANISOTROPIC MELT PHASE DERIVED FROM 6-HYDROXY-2-NAPHTHOIC ACID, DICARBOXYLIC ACID AND AROMATIC MONOMER CAPABLE OF FORMING AN AMIDE LINKAGE | CELANESE CORPORATION (US) | 1985-04-03 | — | — | EP | disclosed |
| EP-0007715-B1 | THERMOTROPIC POLYESTERAMIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-02-29 | — | — | EP | disclosed |
| EP-0053940-A1 | Poly(ester-amide) capable of forming an anisotropic melt phase derived from 6-hydroxy-2-naphthoic acid, dicarboxylic acid and aromatic monomer capable of forming an amide linkage | CELANESE CORPORATION (US) | 1982-06-16 | — | — | EP | disclosed |
| US-4330457-A | Poly(ester-amide) capable of forming an anisotropic melt phase derived from 6-hydroxy-2-naphthoic acid, dicarboxylic acid, and aromatic monomer capable of forming an amide linkage | CELANESE CORPORATION (US) | 1982-05-18 | — | — | US | disclosed |