SCHEMBL2171233

SCHEMBL2171233

C=CCc1nc2ccccc2s1.CCCCCCC(C)Oc1nc2ccccc2s1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.41
NPC1 O15118 7/20 0.38
UBE2T Q9NPD8 1/20 0.36
ASIC3 Q9UHC3 1/20 0.36
SMN1; SMN2 Q16637 7/20 0.36
MAPT P10636 6/20 0.36
ALDH1A1 P00352 4/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
LMNA P02545 2/20 0.36
CYP1A2 P05177 2/20 0.36
CYP2C19 P33261 2/20 0.36
HTT P42858 1/20 0.36
GAA P10253 2/20 0.35
KDM4E B2RXH2 1/20 0.35
RAB9A P51151 6/20 0.35
MAPK1 P28482 1/20 0.35
LOXL2 Q9Y4K0 1/20 0.35
PKM P14618 2/20 0.35
TP53 P04637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12371902 0.88 L3MBTL1 (0.41) L3MBTL1NPC1SMN1; SMN2MAPTALDH1A1
SCHEMBL30423386 0.88 L3MBTL1 (0.41) L3MBTL1NPC1SMN1; SMN2MAPTALDH1A1
SCHEMBL2173022 0.87 L3MBTL1 (0.42) L3MBTL1NPC1SMN1; SMN2MAPTALDH1A1
SCHEMBL12371903 0.78 LOXL2 (0.44) L3MBTL1NPC1UBE2TASIC3SMN1; SMN2
SCHEMBL30422957 0.78 LOXL2 (0.44) L3MBTL1NPC1UBE2TASIC3SMN1; SMN2
SCHEMBL3800420 0.77 PTGS2 (0.40) L3MBTL1NPC1SMN1; SMN2MAPTALDH1A1
SCHEMBL3424669 0.75 UBE2T (0.59) L3MBTL1NPC1UBE2TASIC3SMN1; SMN2
Fluoride SCHEMBL2461456 0.74 UBE2T (0.58) L3MBTL1NPC1UBE2TASIC3SMN1; SMN2
SCHEMBL18013356 0.73 LOXL2 (0.46) L3MBTL1UBE2TASIC3SMN1; SMN2MAPT
SCHEMBL12371895 0.69 PTGS1 (0.57) L3MBTL1NPC1SMN1; SMN2ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3464446-B1 TWO-PART CYANOACRYLATE CURABLE ADHESIVE SYSTEM Henkel IP & Holding GmbH (DE) 2021-06-23 EP claimed
EP-3464446-A1 TWO-PART CYANOACRYLATE CURABLE ADHESIVE SYSTEM Henkel IP & Holding GmbH (DE) 2019-04-10 EP claimed
US-10100235-B2 Two-part cyanoacrylate curable adhesive system Henkel IP & Holding GmbH (DE) 2018-10-16 US claimed
WO-2017202698-A1 TWO-PART CYANOACRYLATE CURABLE ADHESIVE SYSTEM Henkel IP & Holding GmbH (DE) 2017-11-30 WO claimed
US-20170335151-A1 TWO-PART CYANOACRYLATE CURABLE ADHESIVE SYSTEM HENKEL AG & CO. KGAA (DE) 2017-11-23 US claimed
EP-2346956-A1 ACTIVATORS FOR TWO PART CYANOACRYLATE ADHESIVES Loctite (R & D) Limited (IE) 2011-07-27 EP claimed
WO-2010046412-A1 ACTIVATORS FOR TWO PART CYANOACRYLATE ADHESIVES LOCTITE (R & D) LIMITED (IE) 2010-04-29 WO claimed
EP-3464446-B1 TWO-PART CYANOACRYLATE CURABLE ADHESIVE SYSTEM Henkel IP & Holding GmbH (DE) 2021-06-23 EP disclosed
EP-3464446-A1 TWO-PART CYANOACRYLATE CURABLE ADHESIVE SYSTEM Henkel IP & Holding GmbH (DE) 2019-04-10 EP disclosed
US-10100235-B2 Two-part cyanoacrylate curable adhesive system Henkel IP & Holding GmbH (DE) 2018-10-16 US disclosed
WO-2017202698-A1 TWO-PART CYANOACRYLATE CURABLE ADHESIVE SYSTEM Henkel IP & Holding GmbH (DE) 2017-11-30 WO disclosed
US-20170335151-A1 TWO-PART CYANOACRYLATE CURABLE ADHESIVE SYSTEM HENKEL AG & CO. KGAA (DE) 2017-11-23 US disclosed