Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.35 |
| ▸ | PRKACA | P17612 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | PRKACG | P22612 | 1/20 | 0.35 |
| ▸ | PRKACB | P22694 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3991824 | 0.82 | PARP1 (0.40) | ACHEPDPK1NCF1DCPSTLR8 | |
| SCHEMBL21712387 | 0.79 | DCPS (0.54) | ACHEHTR1AHTR2BMAPTALDH1A1 | |
| SCHEMBL29526654 | 0.76 | ADORA3 (0.47) | ACHEMAPTGAAALDH1A1RAB9A | |
| SCHEMBL1233223 | 0.76 | ADORA3 (0.47) | ACHEMAPTGAAALDH1A1RAB9A | |
| SCHEMBL3990704 | 0.75 | TLR7 (0.41) | HTR2BDCPSDHFRTLR8TLR7 | |
| Hydrochloric Acid SCHEMBL5572086 | 0.74 | ADORA3 (0.46) | ACHEMAPTGAAALDH1A1RAB9A | |
| Hydrochloric Acid SCHEMBL3995097 | 0.73 | TLR8 (0.45) | TLR8TLR7 | |
| SCHEMBL5568387 | 0.72 | KCNH2 (0.33) | TLR8TLR7 | |
| Hydrochloric Acid SCHEMBL5572201 | 0.72 | KCNH2 (0.32) | TLR8TLR7 | |
| SCHEMBL23421716 | 0.71 | ACHE (0.39) | ACHEGAAALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11834448-B2 | 2-amino-quinoline derivatives | BIRDIE BIOPHARMACEUTICALS, INC. (KY) | 2023-12-05 | — | — | US | claimed |
| EP-3615539-B1 | 2-AMINO-QUINOLINE DERIVATIVES | BIRDIE BIOPHARMACEUTICALS INC (KY) | 2023-08-09 | — | — | EP | claimed |
| US-20200055851-A1 | 2-AMINO-QUINOLINE DERIVATIVES | BIRDIE BIOPHARMACEUTICALS, INC. (KY) | 2020-02-20 | — | — | US | claimed |
| CN-110637018-A | 2-amino-quinoline derivatives | 博笛生物科技有限公司 | 2019-12-31 | — | — | CN | claimed |
| US-11834448-B2 | 2-amino-quinoline derivatives | BIRDIE BIOPHARMACEUTICALS, INC. (KY) | 2023-12-05 | — | — | US | disclosed |
| US-11834448-B2 | 2-amino-quinoline derivatives | BIRDIE BIOPHARMACEUTICALS, INC. (KY) | 2023-12-05 | — | — | US | disclosed |
| US-11834448-B2 | 2-amino-quinoline derivatives | BIRDIE BIOPHARMACEUTICALS, INC. (KY) | 2023-12-05 | — | — | US | disclosed |
| EP-3615539-B1 | 2-AMINO-QUINOLINE DERIVATIVES | BIRDIE BIOPHARMACEUTICALS INC (KY) | 2023-08-09 | — | — | EP | disclosed |
| EP-3615539-B1 | 2-AMINO-QUINOLINE DERIVATIVES | BIRDIE BIOPHARMACEUTICALS INC (KY) | 2023-08-09 | — | — | EP | disclosed |
| US-11053240-B2 | 2-amino-quinoline derivatives | BIRDIE BIOPHARMACEUTICALS, INC. (KY) | 2021-07-06 | — | — | US | disclosed |
| US-11053240-B2 | 2-amino-quinoline derivatives | BIRDIE BIOPHARMACEUTICALS, INC. (KY) | 2021-07-06 | — | — | US | disclosed |
| US-20200055851-A1 | 2-AMINO-QUINOLINE DERIVATIVES | BIRDIE BIOPHARMACEUTICALS, INC. (KY) | 2020-02-20 | — | — | US | disclosed |
| US-20200055851-A1 | 2-AMINO-QUINOLINE DERIVATIVES | BIRDIE BIOPHARMACEUTICALS, INC. (KY) | 2020-02-20 | — | — | US | disclosed |
| CN-110637018-A | 2-amino-quinoline derivatives | 博笛生物科技有限公司 | 2019-12-31 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11053240-B2 | 2-amino-quinoline derivatives | TLR7, TLR8, TLR1 | CYP1A2 1011/4885ACHE 3149/4885CHRM5 442/4885 |
| US-20200055851-A1 | 2-AMINO-QUINOLINE DERIVATIVES | TLR7, TLR8, TLR1 | CYP1A2 1011/4885ACHE 3149/4885CHRM5 442/4885 |
| US-11834448-B2 | 2-amino-quinoline derivatives | TLR7, TLR8, TLR1 | CYP1A2 1011/4885ACHE 3149/4885CHRM5 442/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.