Sugi Predict

Sugi Predict / Compounds / SCHEMBL519390

SCHEMBL519390

SCHEMBL519390

COC(=O)c1cc(Br)c[nH]1

nearest known ligand 0.61

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ CREBBP Q92793 1/20 0.61
▸ BAZ2B Q9UIF8 1/20 0.54
▸ BAZ2A Q9UIF9 1/20 0.54
▸ ALDH1A1 P00352 4/20 0.50
▸ GAA P10253 2/20 0.46
▸ LMNA P02545 1/20 0.46
▸ NR4A2 P43354 1/20 0.46
▸ PKM P14618 1/20 0.45
▸ KMT2A Q03164 2/20 0.44
▸ MAPK1 P28482 1/20 0.43
▸ CYP1A2 P05177 1/20 0.43
▸ XDH P47989 1/20 0.42
▸ DAO P14920 1/20 0.42
▸ MEN1 O00255 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12493614 0.83 CREBBP (0.61) CREBBPBAZ2BBAZ2AALDH1A1GAA
SCHEMBL16472424 0.81 CREBBP (0.58) CREBBPBAZ2BBAZ2AALDH1A1NR4A2
SCHEMBL2544551 0.79 CREBBP (0.51) CREBBPBAZ2BBAZ2AALDH1A1GAA
SCHEMBL5202768 0.78 BAZ2B (0.56) BAZ2BBAZ2AALDH1A1GAALMNA
SCHEMBL21060866 0.78 BAZ2B (0.56) BAZ2BBAZ2AALDH1A1GAALMNA
SCHEMBL162449 0.78 BAZ2B (0.56) BAZ2BBAZ2AALDH1A1GAALMNA
SCHEMBL70354 0.78 BAZ2B (0.71) BAZ2BBAZ2AALDH1A1GAALMNA
SCHEMBL15176658 0.77 — —
SCHEMBL23718091 0.76 CREBBP (1.00) CREBBPPKMKMT2ADAO
SCHEMBL20763689 0.76 BAZ2B (0.54) BAZ2BBAZ2AALDH1A1GAALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 510 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117567498-A Sodium hydride suspension and application thereof in flow chemical reaction 武汉药明康德新药开发有限公司 2024-02-20 — — CN claimed
CN-117069063-A Sodium hydride suspension and application thereof in flow chemical reaction 武汉药明康德新药开发有限公司 2023-11-17 — — CN claimed
CN-117062813-B Polycyclic compound and application thereof 四川汇宇制药股份有限公司 2026-05-19 — — CN disclosed
US-12624043-B2 Compositions useful for treating disorders related to kit BLUEPRINT MEDICINES CORPORATION (US) 2026-05-12 — — US disclosed
EP-4725560-A2 ANTI-B7H3 ANTIBODIES FOR THE PREPARATION OF ANTIBODY DRUG CONJUGATES (ADCS) OF KSP INHIBITORS Bayer Pharma Aktiengesellschaft (DE) 2026-04-15 — — EP disclosed
US-20260078131-A1 PYRROLO-PYRIDAZINE INHIBITORS OF JAK2 AJAX THERAPEUTICS INC (US) 2026-03-19 — — US disclosed
US-12569485-B2 SMARCA inhibitors and uses thereof KYMERA THERAPEUTICS, INC. (US) 2026-03-10 — — US disclosed
EP-4702017-A1 SARM1 MODULATORS, PREPARATIONS, AND USES THEREOF Sironax Ltd (KY) 2026-03-04 — — EP disclosed
US-20260008780-A1 SUBSTITUTED 3,4-DIHYDROISOQUINOLIN-1(2H)-ONE DERIVATIVES AND RELATED USES NODTHERA LTD (GB) 2026-01-08 — — US disclosed
US-20260008760-A1 DIPEPTIDYL PEPTIDASE 1 INHIBITORS AND USES THEREOF INSMED INCORPORATED 2026-01-08 — — US disclosed
US-12492210-B2 Tricyclic compounds and their use HUTCHISON MEDIPHARMA LIMITED (CN) 2025-12-09 — — US disclosed
US-20030153568-A1 Benzothiazole derivatives BASF AKTIENGESELLSCHAFT LUDWIGSHAFEN, GERMANY 2003-08-14 — — US disclosed
CN-1422262-A 2-benzothiazolyl urea derivatives and their use as protein kinase inhibitors ABBOTT GMBH & CO KG (DE) 2003-06-04 — — CN disclosed
EP-1254123-A1 2-BENZOTHIAZOLYL UREA DERIVATIVES AND THEIR USE AS PROTEIN KINASE INHIBITORS Abbott GmbH & Co. KG (DE) 2002-11-06 — — EP disclosed
WO-2001057008-A1 2-BENZOTHIAZOLYL UREA DERIVATIVES AND THEIR USE AS PROTEIN KINASE INHIBITORS ABBOTT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG & COMPANY KOMMANDITGESELLSCHAFT (DE) 2001-08-09 — — WO disclosed
EP-0039239-B1 HERBICIDAL PYRROLE SULFONAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1986-02-26 — — EP disclosed
US-4557752-A Herbicidal sulfonamides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1985-12-10 — — US disclosed
US-4473394-A HERBICIDES E. I. DUPONT DE NEMOURS & COMPANY (US) 1984-09-25 — — US disclosed
US-4368067-A PRE-AND POSTEMERGENCE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1983-01-11 — — US disclosed
EP-0039239-A2 Herbicidal pyrrole sulfonamides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1981-11-04 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260078131-A1 PYRROLO-PYRIDAZINE INHIBITORS OF JAK2 JAK2, JAK1, JAK3 CREBBP 2243/4885BAZ2B 405/4885BAZ2A 377/4885
US-12624043-B2 Compositions useful for treating disorders related to kit KIT, RET, SLC26A4 CREBBP 709/4885BAZ2B 3595/4885BAZ2A 4040/4885
US-20260008760-A1 DIPEPTIDYL PEPTIDASE 1 INHIBITORS AND USES THEREOF DPP9, DPP7, DPP4 CREBBP 4011/4885BAZ2B 2189/4885BAZ2A 2874/4885
US-12492210-B2 Tricyclic compounds and their use CYP2C8, CYP11B2, CYP3A7 CREBBP 1968/4885BAZ2B 3218/4885BAZ2A 2841/4885
US-20260008780-A1 SUBSTITUTED 3,4-DIHYDROISOQUINOLIN-1(2H)-ONE DERIVATIVES AND RELATED USES NOD1, NLRP3, CASP1 CREBBP 4415/4885BAZ2B 1096/4885BAZ2A 812/4885
US-20030153568-A1 Benzothiazole derivatives TK1, FLT1, CDK1 CREBBP 1522/4885BAZ2B 1528/4885BAZ2A 2274/4885
US-12569485-B2 SMARCA inhibitors and uses thereof SMARCC1, SMARCC2, SMARCA2 CREBBP 1450/4885BAZ2B 140/4885BAZ2A 93/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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