Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PTPRF | P10586 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21715397 | 0.88 | KDM4E (0.63) | KDM4EALDH1A1HPGDACHECYP19A1 | |
| SCHEMBL21715389 | 0.81 | KDM4E (0.45) | KDM4EALDH1A1HPGDACHECYP19A1 | |
| SCHEMBL4119937 | 0.79 | ALDH1A1 (0.60) | KDM4EALDH1A1HPGDACHEHSD17B10 | |
| SCHEMBL21715425 | 0.74 | KDM4E (0.38) | KDM4EALDH1A1HPGDACHECYP19A1 | |
| SCHEMBL21715408 | 0.68 | ALDH1A1 (0.57) | KDM4EALDH1A1HPGDACHECYP19A1 | |
| SCHEMBL9345242 | 0.68 | ADRA1A (0.62) | ADRA1ACYP1A2HTR6 | |
| SCHEMBL4128606 | 0.68 | KDM4E (0.42) | KDM4EALDH1A1HPGDACHEHSD17B10 | |
| SCHEMBL354324 | 0.67 | KDM4E (1.00) | KDM4EALDH1A1HPGDACHEPARP1 | |
| SCHEMBL611321 | 0.65 | ALDH1A1 (0.81) | KDM4EALDH1A1HPGDACHEPARP1 | |
| SCHEMBL6112770 | 0.65 | ALDH1A1 (0.81) | KDM4EALDH1A1HPGDACHEPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10807932-B2 | Benzosuberene analogues and related compounds with activity as anticancer agents | BAYLOR UNIVERSITY (US) | 2020-10-20 | — | — | US | disclosed |
| US-10807932-B2 | Benzosuberene analogues and related compounds with activity as anticancer agents | BAYLOR UNIVERSITY (US) | 2020-10-20 | — | — | US | disclosed |
| US-20200055805-A1 | BENZOSUBERENE ANALOGUES AND RELATED COMPOUNDS WITH ACTIVITY AS ANTICANCER AGENTS | BAYLOR UNIVERSITY (US) | 2020-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200055805-A1 | BENZOSUBERENE ANALOGUES AND RELATED COMPOUNDS WITH ACTIVITY AS ANTICANCER AGENTS | TUBB1, TUBB3, TUBB | KDM4E 3545/4885ALDH1A1 2239/4885HPGD 1485/4885 |
| US-10807932-B2 | Benzosuberene analogues and related compounds with activity as anticancer agents | TUBB1, TUBB3, TUBB | KDM4E 3545/4885ALDH1A1 2239/4885HPGD 1485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.