Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 5/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11122001 | 0.81 | TSHR (0.41) | CHRNB2CHRNA4TSHRMAPK1HSD17B10 | |
| SCHEMBL3686781 | 0.78 | — | — | |
| SCHEMBL21570869 | 0.77 | TSHR (0.48) | TSHRALDH1A1 | |
| SCHEMBL12975855 | 0.76 | TSHR (0.37) | CHRNB2CHRNA4TSHRCA12CA1 | |
| SCHEMBL27803239 | 0.76 | KDM4E (0.40) | TSHRMAPK1ALDH1A1KDM4E | |
| SCHEMBL20718324 | 0.75 | CHRNB2 (0.66) | CHRNB2CHRNA4CHRNB4CHRNA3CA12 | |
| SCHEMBL2056762 | 0.75 | TSHR (0.52) | TSHRALDH1A1 | |
| SCHEMBL2116165 | 0.75 | — | — | |
| SCHEMBL2056773 | 0.75 | TSHR (0.52) | TSHRHSD17B10ALDH1A1 | |
| SCHEMBL5924841 | 0.74 | HPGD (0.57) | TSHRMAPK1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10668676-B2 | Ophthalmic devices | BAUSCH & LOMB INCORPORATED (US) | 2020-06-02 | — | — | US | disclosed |
| US-20200047437-A1 | OPHTHALMIC DEVICES | MEDICIS PHARMACEUTICAL CORPORATION | 2020-02-13 | — | — | US | disclosed |