SCHEMBL2171680

SCHEMBL2171680

N#CCCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9577681 1.00 ALDH1A1 (0.32) ALDH1A1TDP1LMNA
SCHEMBL9192100 1.00 ALDH1A1 (0.32) ALDH1A1TDP1LMNA
SCHEMBL8096641 0.98 ALDH1A1 (0.33) ALDH1A1TDP1
SCHEMBL7226896 0.84 TSHR (0.33) ALDH1A1TDP1
SCHEMBL8422067 0.81 ALDH1A1 (0.32) ALDH1A1TDP1
SCHEMBL9438152 0.79 ALDH1A1 (0.44) ALDH1A1TDP1
SCHEMBL3175635 0.76 THRB (0.31) LMNA
SCHEMBL9315228 0.76 THRB (0.31) LMNA
SCHEMBL7643011 0.76 LMNA (0.42) LMNA
SCHEMBL7641162 0.76 LMNA (0.42) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2346923-B1 FLUORINATED POLYOXYALKYLENE GLYCOL DIAMIDE SURFACTANTS DU PONT (US) 2012-11-21 EP disclosed
US-8026289-B2 Fluorinated polyoxyalkylene glycol diamide surfactants E.I. DU PONT DE NEMOURS AND COMPANY (US) 2011-09-27 US disclosed
EP-2346923-A2 FLUORINATED POLYOXYALKYLENE GLYCOL DIAMIDE SURFACTANTS E. I. du Pont de Nemours and Company (US) 2011-07-27 EP disclosed
WO-2010048248-A2 FLUORINATED POLYOXYALKYLENE GLYCOL DIAMIDE SURFACTANTS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-04-29 WO disclosed
US-20100099839-A1 FLUORINATED POLYOXYALKYLENE GLYCOL DIAMIDE SURFACTANTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2010-04-22 US disclosed