SCHEMBL9315228

SCHEMBL9315228

O=[C]CCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3175635 1.00 THRB (0.31) THRBLMNA
SCHEMBL4809229 0.90
SCHEMBL9577681 0.76 ALDH1A1 (0.32) LMNA
SCHEMBL9192100 0.76 ALDH1A1 (0.32) LMNA
SCHEMBL2171680 0.76 ALDH1A1 (0.32) LMNA
SCHEMBL7641162 0.76 LMNA (0.42) THRBLMNA
SCHEMBL7643011 0.76 LMNA (0.42) THRBLMNA
SCHEMBL4918625 0.75 CA2 (0.36) THRBLMNA
SCHEMBL9316019 0.75 CA2 (0.36) THRBLMNA
SCHEMBL8096641 0.73 ALDH1A1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5306615-A Liquid perfluorocarbon support; fluorinated isocyanate anchor groups E. I. DU PONT DE NEMOURS AND COMPANY (US) 1994-04-26 US disclosed
US-5276146-A Ligand attached to support with isocyanate anchor E. I. DU PONT DE NEMOURS AND COMPANY (US) 1994-01-04 US disclosed
US-5268456-A Immobilizing a protein; bonding to ligand E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-12-07 US disclosed
US-5268307-A Dissolving a perfluoroisocyanate emulsifier with ligand or binder E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-12-07 US disclosed