Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 3/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 2/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 2/20 | 0.33 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.33 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.33 |
| ▸ | WNT3A | P56704 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2171763 | 0.81 | XDH (0.46) | CYP11B2GRM2XDHSLC22A12ABL1 | |
| SCHEMBL2171685 | 0.79 | S1PR3 (0.42) | XDHS1PR3WNT3A | |
| SCHEMBL2171775 | 0.77 | P2RX3 (0.43) | XDH | |
| SCHEMBL2172263 | 0.72 | NSD2 (0.37) | CYP11B2SLC22A12S1PR3 | |
| SCHEMBL2172429 | 0.70 | P2RX3 (0.53) | — | |
| SCHEMBL2172422 | 0.70 | P2RX3 (0.53) | — | |
| SCHEMBL1495543 | 0.70 | TDP1 (0.45) | GRM2XDHCYP46A1 | |
| SCHEMBL2170462 | 0.70 | S1PR3 (0.41) | XDHS1PR3 | |
| SCHEMBL7676386 | 0.67 | LRRK2 (0.51) | CYP11B2SLC22A12ABL1 | |
| SCHEMBL2172000 | 0.67 | S1PR3 (0.40) | XDHS1PR3WNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346825-A2 | MODULATORS OF P2X3 RECEPTOR ACTIVITY | Evotec AG (DE) | 2011-07-27 | — | — | EP | disclosed |