SCHEMBL21717820

SCHEMBL21717820

CC(C)c1ccc(-c2cc3c4ccccc4n4c5cc6ccccc6cc5c(c2)c34)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 1/20 0.34
TNKS O95271 1/20 0.34
PARP1 P09874 1/20 0.34
TNKS2 Q9H2K2 1/20 0.34
HDAC6 Q9UBN7 1/20 0.34
PARP2 Q9UGN5 1/20 0.34
MAPT P10636 2/20 0.33
UGT2B7 P16662 1/20 0.33
RAB9A P51151 1/20 0.33
PAX8 Q06710 1/20 0.33
NOD2 Q9HC29 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
KIF11 P52732 1/20 0.33
TP53 P04637 1/20 0.33
GAA P10253 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
NPY5R Q15761 1/20 0.33
CASR P41180 1/20 0.33
PIK3CD O00329 1/20 0.32
EGFR P00533 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19563803 0.95 UGT2B7 (0.37) DHODHTNKSPARP1TNKS2HDAC6
SCHEMBL21710686 0.90 TNKS (0.39) DHODHTNKSPARP1TNKS2HDAC6
SCHEMBL21710721 0.90 PTPN5 (0.35) DHODHTNKSPARP1TNKS2HDAC6
SCHEMBL21717864 0.88 UGT2B7 (0.34) MAPTUGT2B7L3MBTL1KIF11SMN1; SMN2
SCHEMBL21710691 0.86 NTSR1 (0.33) NPY5R
SCHEMBL21718047 0.86 ESR1 (0.38) MAPTL3MBTL1TP53GAANPY5R
SCHEMBL19563886 0.85 CASR (0.35) UGT2B7CASR
SCHEMBL19563761 0.85 LMNA (0.34) UGT2B7KIF11PIK3CDKDM4EALDH1A1
SCHEMBL19563926 0.85 KDM4E (0.34) UGT2B7L3MBTL1KIF11PIK3CDRXFP1
SCHEMBL21717366 0.84 ESR1 (0.39) MAPTL3MBTL1GAANPY5RPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11723272-B2 Organic electroluminescence element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2023-08-08 US disclosed
US-11723272-B2 Organic electroluminescence element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2023-08-08 US disclosed
US-20210005826-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO., LTD. (JP) 2021-01-07 US disclosed
US-20210005825-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2021-01-07 US disclosed
US-20200365812-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2020-11-19 US disclosed
US-20200052225-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2020-02-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200052225-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE LEF1, L1CAM, ESR2 DHODH 3330/4885TNKS 3652/4885PARP1 1297/4885
US-20210005825-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE OR51E2, CD99, CTNND1 DHODH 764/4885TNKS 4658/4885PARP1 3214/4885
US-20210005826-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC APPARATUS EML4, EBPL, LEF1 DHODH 644/4885TNKS 4428/4885PARP1 3441/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.