SCHEMBL21718147

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21718143	0.91	ENPP3 (0.41)	ENPP3PGRCHEK1MAP4K4MEN1
	SCHEMBL21718058	0.90	ENPP3 (0.42)	ENPP3PGRCHEK1PTGER4CA1
	SCHEMBL22679619	0.89	ENPP3 (0.48)	ENPP3CA1CA2MEN1KMT2A
	SCHEMBL21710647	0.89	PTGER4 (0.41)	ENPP3PGRCHEK1PTGER4MAP4K4
	SCHEMBL19563850	0.89	ENPP3 (0.40)	ENPP3PGRCHEK1PTGER4CA1
	SCHEMBL21717834	0.86	CA1 (0.40)	ENPP3PGRPTGER4CA1CA2
	SCHEMBL21718165	0.86	ESR1 (0.38)	—
	SCHEMBL21718140	0.86	ESR1 (0.38)	—
	SCHEMBL21710725	0.85	ESR1 (0.37)	—
	SCHEMBL25005683	0.84	CYP17A1 (0.39)	ENPP3PGRCHEK1PDPK1KAT6A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.