Glycyclamide

Glycyclamide

SCHEMBL21722119

Cc1ccc(S(=O)(=O)NC(=O)NC2CCCCC2)cc1.N

nearest known ligand 0.97

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 1/20 0.97
ALDH1A1 P00352 5/20 0.73
TSHR P16473 3/20 0.73
LMNA P02545 3/20 0.73
THRB P10828 1/20 0.73
BLM P54132 1/20 0.73
TDP1 Q9NUW8 1/20 0.73
GAA P10253 2/20 0.71
KCNH2 Q12809 1/20 0.71
HTT P42858 1/20 0.62
HSD17B10 Q99714 1/20 0.62
CYP3A4 P08684 2/20 0.61
NPC1 O15118 1/20 0.58
RAB9A P51151 1/20 0.58
EPHX1 P07099 1/20 0.58
KDM4E B2RXH2 1/20 0.58
TP53 P04637 1/20 0.58
GLA P06280 1/20 0.58
MAPT P10636 1/20 0.58
ALOX12 P18054 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Heptolamide SCHEMBL1814750 0.99 ADORA3 (1.00) ADORA3ALDH1A1TSHRLMNATHRB
Glycyclamide SCHEMBL49386 0.99 ADORA3 (1.00) ADORA3ALDH1A1TSHRLMNATHRB
Glyoctamide SCHEMBL667731 0.99 ADORA3 (1.00) ADORA3ALDH1A1TSHRLMNATHRB
Tolpentamide SCHEMBL2109411 0.97 ADORA3 (0.97) ADORA3ALDH1A1TSHRLMNATHRB
SCHEMBL5931113 0.86 ADORA3 (0.77) ADORA3ALDH1A1TSHRLMNATHRB
Acetohexamide SCHEMBL15669221 0.84 ALDH1A1 (1.00) ADORA3ALDH1A1TSHRLMNATHRB
Acetohexamide SCHEMBL37620 0.84 ALDH1A1 (1.00) ADORA3ALDH1A1TSHRLMNATHRB
SCHEMBL23736042 0.84 ADORA3 (0.74) ADORA3ALDH1A1TSHRLMNATHRB
SCHEMBL23007557 0.84 ADORA3 (0.74) ADORA3ALDH1A1TSHRLMNATHRB
SCHEMBL24162711 0.84 PPARG (0.76) ADORA3ALDH1A1TSHRLMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020034181-A1 QUATERNARY TRIPHENYLPHOSPHONIUM SALT COMPOUND, PREPARATION METHOD THEREFOR, AND USES THEREOF 中国农业大学 2020-02-20 WO disclosed