Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12675581 | 0.78 | GAA (0.61) | KDM4EGAAMAPTL3MBTL1DYRK1A | |
| SCHEMBL21731427 | 0.77 | APP (0.34) | KDM4EL3MBTL1ALDH1A1CYP2C19LMNA | |
| SCHEMBL21731373 | 0.75 | GAA (0.43) | KDM4EGAAMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL7970286 | 0.74 | KMT2A (0.43) | KDM4EMAPTL3MBTL1ALDH1A1CYP3A4 | |
| SCHEMBL12675380 | 0.74 | KDM4E (0.56) | KDM4EGAAMAPTL3MBTL1DYRK1A | |
| SCHEMBL21731414 | 0.74 | KDM4E (0.41) | KDM4EGAAMAPTL3MBTL1DYRK1A | |
| SCHEMBL21682617 | 0.74 | MAPT (0.47) | KDM4EMAPTALDH1A1LMNAKMT2A | |
| SCHEMBL21731428 | 0.72 | KDM4E (0.43) | KDM4EGAAMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL21731372 | 0.72 | GAA (0.40) | KDM4EGAAMAPTL3MBTL1DYRK1A | |
| SCHEMBL21723209 | 0.70 | KDM4E (0.39) | KDM4EGAAMAPTL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020035565-A1 | PESTICIDALLY-ACTIVE MESOIONIC BICYCLIC HETEROAROMATIC COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2020-02-20 | — | — | WO | disclosed |
| WO-2020035565-A1 | PESTICIDALLY-ACTIVE MESOIONIC BICYCLIC HETEROAROMATIC COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2020-02-20 | — | — | WO | disclosed |