Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21731428 | 0.87 | KDM4E (0.43) | GAAKDM4EMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL21723209 | 0.83 | KDM4E (0.39) | GAAKDM4EMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL21731372 | 0.83 | GAA (0.40) | GAAKDM4EMAPTL3MBTL1KCNH2 | |
| SCHEMBL21731414 | 0.80 | KDM4E (0.41) | GAAKDM4EMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL21682616 | 0.80 | MAPT (0.47) | GAAKDM4EMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL7971464 | 0.79 | GAA (0.45) | GAAKDM4EMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL21731377 | 0.78 | CYP11B1 (0.41) | GAAKDM4EMAPTL3MBTL1 | |
| SCHEMBL21731369 | 0.78 | KMT2A (0.43) | GAAALDH1A1KMT2A | |
| SCHEMBL21731410 | 0.75 | GAA (0.41) | GAAKDM4EMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL21723173 | 0.75 | GAA (0.41) | GAAKDM4EMAPTL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020035565-A1 | PESTICIDALLY-ACTIVE MESOIONIC BICYCLIC HETEROAROMATIC COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2020-02-20 | — | — | WO | disclosed |