Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.32 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21731373 | 0.83 | GAA (0.43) | GAAKDM4EMAPTL3MBTL1KCNH2 | |
| SCHEMBL21731428 | 0.81 | KDM4E (0.43) | GAAKDM4EMAPTL3MBTL1KMT2A | |
| SCHEMBL21723209 | 0.78 | KDM4E (0.39) | GAAKDM4EMAPTL3MBTL1CYP3A4 | |
| SCHEMBL21682616 | 0.76 | MAPT (0.47) | GAAKDM4EMAPTL3MBTL1KMT2A | |
| SCHEMBL7971464 | 0.76 | GAA (0.45) | GAAKDM4EMAPTL3MBTL1KMT2A | |
| SCHEMBL21731377 | 0.75 | CYP11B1 (0.41) | GAAKDM4EMAPTL3MBTL1ITGB1 | |
| SCHEMBL21731369 | 0.75 | KMT2A (0.43) | GAAKMT2AALDH1A1DYRK1A | |
| SCHEMBL21723173 | 0.75 | GAA (0.41) | GAAKDM4EMAPTL3MBTL1KMT2A | |
| SCHEMBL21731414 | 0.74 | KDM4E (0.41) | GAAKDM4EMAPTL3MBTL1CYP3A4 | |
| SCHEMBL21731410 | 0.72 | GAA (0.41) | GAAKDM4EMAPTL3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020035565-A1 | PESTICIDALLY-ACTIVE MESOIONIC BICYCLIC HETEROAROMATIC COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2020-02-20 | — | — | WO | disclosed |