Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 6/20 | 0.42 |
| ▸ | ITGA5 | P08648 | 6/20 | 0.42 |
| ▸ | APP | P05067 | 4/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.40 |
| ▸ | ITGAV | P06756 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21731373 | 0.87 | GAA (0.43) | KDM4EGAAMAPTL3MBTL1APP | |
| SCHEMBL21682616 | 0.83 | MAPT (0.47) | KDM4EGAAMAPTL3MBTL1KMT2A | |
| SCHEMBL7971464 | 0.82 | GAA (0.45) | KDM4EGAAMAPTL3MBTL1KMT2A | |
| SCHEMBL21731377 | 0.82 | CYP11B1 (0.41) | KDM4EGAAMAPTL3MBTL1ITGB1 | |
| SCHEMBL21723209 | 0.82 | KDM4E (0.39) | KDM4EGAAMAPTL3MBTL1APP | |
| SCHEMBL21731372 | 0.81 | GAA (0.40) | KDM4EGAAMAPTL3MBTL1ITGB1 | |
| SCHEMBL21731369 | 0.79 | KMT2A (0.43) | GAAKMT2AALDH1A1 | |
| SCHEMBL21731410 | 0.78 | GAA (0.41) | KDM4EGAAMAPTL3MBTL1KMT2A | |
| SCHEMBL17674597 | 0.78 | GAA (0.41) | KDM4EGAAMAPTL3MBTL1KMT2A | |
| SCHEMBL21723173 | 0.78 | GAA (0.41) | KDM4EGAAMAPTL3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020035565-A1 | PESTICIDALLY-ACTIVE MESOIONIC BICYCLIC HETEROAROMATIC COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2020-02-20 | — | — | WO | disclosed |