Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21723181 | 0.77 | KDM4E (0.47) | APPKDM4EKMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL21682617 | 0.76 | MAPT (0.47) | KDM4EKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL7970286 | 0.74 | KMT2A (0.43) | KDM4EKMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL21682615 | 0.72 | KDM4E (0.40) | APPKDM4EKMT2AMEN1L3MBTL1 | |
| SCHEMBL21682636 | 0.68 | L3MBTL1 (0.37) | KDM4EKMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL24287822 | 0.68 | KCNH3 (0.40) | — | |
| SCHEMBL4019956 | 0.64 | HRH4 (0.38) | ALDH1A1LMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8447855 | 0.63 | — | — | |
| SCHEMBL21731373 | 0.61 | GAA (0.43) | APPKDM4EKMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL18047238 | 0.61 | CXCR4 (0.55) | KDM4EKMT2AMEN1ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020035565-A1 | PESTICIDALLY-ACTIVE MESOIONIC BICYCLIC HETEROAROMATIC COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2020-02-20 | — | — | WO | disclosed |