Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21723975 | 0.82 | NPC1 (0.36) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL21724321 | 0.79 | PDE4D (0.32) | ALDH1A1LMNAHPGD | |
| SCHEMBL21724766 | 0.78 | TACR1 (0.38) | NPC1RAB9A | |
| SCHEMBL21724030 | 0.77 | ALDH1A1 (0.36) | RAB9AALDH1A1LMNA | |
| SCHEMBL21724331 | 0.77 | PYCR1 (0.39) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL21723902 | 0.76 | MTOR (0.38) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL21723776 | 0.76 | — | — | |
| SCHEMBL21723914 | 0.76 | PYCR1 (0.41) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL21723969 | 0.76 | ALDH1A1 (0.39) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL21724804 | 0.76 | DAO (0.43) | NPC1RAB9AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020035826-A1 | 1,2-DITHIOLONE COMPOUNDS AND USE THEREOF | PI INDUSTRIES LTD. (IN) | 2020-02-20 | — | — | WO | claimed |
| WO-2020035826-A1 | 1,2-DITHIOLONE COMPOUNDS AND USE THEREOF | PI INDUSTRIES LTD. (IN) | 2020-02-20 | — | — | WO | disclosed |