Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.33 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21724331 | 0.86 | PYCR1 (0.39) | ALDH1A1CYP3A4KMT2AMEN1CNR1 | |
| SCHEMBL21724804 | 0.85 | DAO (0.43) | ALDH1A1TDP1RAB9ANPC1MAPT | |
| SCHEMBL21723902 | 0.85 | MTOR (0.38) | ALDH1A1CYP3A4KMT2AMEN1GFER | |
| SCHEMBL21723914 | 0.85 | PYCR1 (0.41) | ALDH1A1TSHRTDP1KMT2AMEN1 | |
| SCHEMBL10852766 | 0.84 | RAB9A (0.46) | ALDH1A1TSHRKMT2AMEN1KDM4E | |
| SCHEMBL21723672 | 0.84 | PYCR1 (0.44) | ALDH1A1KMT2AMEN1HDAC1HDAC6 | |
| SCHEMBL21723609 | 0.82 | KMT2A (0.43) | ALDH1A1TSHRKMT2AMEN1KDM4E | |
| SCHEMBL21723648 | 0.82 | ALDH1A1 (0.48) | ALDH1A1TDP1KMT2AMEN1HTT | |
| SCHEMBL21723975 | 0.82 | NPC1 (0.36) | ALDH1A1TSHRTDP1CYP3A4KMT2A | |
| SCHEMBL21724768 | 0.81 | PYCR1 (0.44) | ALDH1A1KMT2AMEN1CNR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020035826-A1 | 1,2-DITHIOLONE COMPOUNDS AND USE THEREOF | PI INDUSTRIES LTD. (IN) | 2020-02-20 | — | — | WO | claimed |
| WO-2020035826-A1 | 1,2-DITHIOLONE COMPOUNDS AND USE THEREOF | PI INDUSTRIES LTD. (IN) | 2020-02-20 | — | — | WO | disclosed |