Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYCR1 | P32322 | 7/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | LSS | P48449 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21724331 | 0.86 | PYCR1 (0.39) | PYCR1HTTALDH1A1KMT2AMEN1 | |
| SCHEMBL21723776 | 0.85 | — | — | |
| SCHEMBL21724804 | 0.85 | DAO (0.43) | PYCR1HTTALDH1A1TAAR1NPC1 | |
| SCHEMBL21723902 | 0.85 | MTOR (0.38) | MAOBHTTALDH1A1KMT2AMEN1 | |
| SCHEMBL21723969 | 0.85 | ALDH1A1 (0.39) | HTTKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL10852766 | 0.84 | RAB9A (0.46) | KDM4EALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL21723672 | 0.84 | PYCR1 (0.44) | PYCR1HTTKDM4EALDH1A1KMT2A | |
| SCHEMBL21724535 | 0.83 | PYCR1 (0.46) | PYCR1TAAR1NPC1MAPT | |
| SCHEMBL21723609 | 0.82 | KMT2A (0.43) | KDM4EALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL21723648 | 0.82 | ALDH1A1 (0.48) | PYCR1HTTALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020035826-A1 | 1,2-DITHIOLONE COMPOUNDS AND USE THEREOF | PI INDUSTRIES LTD. (IN) | 2020-02-20 | — | — | WO | claimed |