Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21724689 | 0.80 | L3MBTL1 (0.52) | MAPTMAPK1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL21724298 | 0.78 | NPSR1 (0.38) | MAPTMAPK1ALDH1A1LMNANR1I2 | |
| SCHEMBL31248428 | 0.78 | USP2 (0.46) | MAPTMAPK1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL31389219 | 0.76 | POLB (0.37) | MAPTMAPK1ALDH1A1LMNANR1I2 | |
| SCHEMBL28653411 | 0.74 | HPGD (0.49) | ALDH1A1LMNANR1I2KDM4EHCRTR1 | |
| SCHEMBL31389220 | 0.74 | KDM4E (0.38) | MAPTMAPK1ALDH1A1LMNAPOLB | |
| SCHEMBL31248443 | 0.74 | TSHR (0.39) | ALDH1A1LMNANPSR1KDM4E | |
| SCHEMBL31389222 | 0.74 | KDM4E (0.38) | MAPTMAPK1ALDH1A1LMNAPOLB | |
| SCHEMBL27855383 | 0.73 | MYC (0.39) | MAPTALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL1396563 | 0.70 | PSIP1 (0.53) | MAPTMAPK1ALDH1A1LMNANR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112930345-A | Novel halo- (3- (phenylsulfonyl) prop-1-ene) pyridine derivatives and uses thereof | 韩国科学技术研究院 | 2021-06-08 | — | — | CN | claimed |
| WO-2020036474-A1 | NOVEL HALO-(3-(PHENYLSULFONYL)PROP-1-ENYL)PYRIDINE DERIVATIVE AND USE THEREOF | 한국과학기술연구원 | 2020-02-20 | — | — | WO | claimed |
| CN-112930345-A | Novel halo- (3- (phenylsulfonyl) prop-1-ene) pyridine derivatives and uses thereof | 韩国科学技术研究院 | 2021-06-08 | — | — | CN | disclosed |
| WO-2020036474-A1 | NOVEL HALO-(3-(PHENYLSULFONYL)PROP-1-ENYL)PYRIDINE DERIVATIVE AND USE THEREOF | 한국과학기술연구원 | 2020-02-20 | — | — | WO | disclosed |