Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | CASP9 | P55211 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21724689 | 0.88 | L3MBTL1 (0.52) | ALDH1A1MAPTSMN1; SMN2HPGDMAPK1 | |
| SCHEMBL15818796 | 0.79 | USP2 (0.55) | USP2PTPN1ABCB1CASP3CASP7 | |
| SCHEMBL15819886 | 0.78 | USP2 (0.53) | USP2PTPN1ABCB1CASP3CASP7 | |
| SCHEMBL21723076 | 0.78 | NPSR1 (0.64) | ALDH1A1NPSR1MAPTSMN1; SMN2HPGD | |
| SCHEMBL21723738 | 0.78 | MAPT (0.37) | ALDH1A1NPSR1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL21724298 | 0.76 | NPSR1 (0.38) | ALDH1A1NPSR1LMNAMAPTMAPK1 | |
| SCHEMBL15818015 | 0.76 | USP2 (0.51) | USP2PTPN1ABCB1CASP3CASP7 | |
| SCHEMBL2010417 | 0.75 | USP2 (0.67) | USP2PTPN1ABCB1CASP3CASP7 | |
| SCHEMBL31389219 | 0.74 | POLB (0.37) | PTPN1ALDH1A1NPSR1LMNAMAPT | |
| SCHEMBL28653411 | 0.72 | HPGD (0.49) | ALDH1A1LMNAHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12234207-B2 | Halo-(3-(phenylsulfonyl)prop-1-enyl)pyridine derivative and use thereof | CUREVERSE INCORPORATED (KR) | 2025-02-25 | — | — | US | claimed |
| CN-112930345-B | Novel halo- (3- (benzenesulfonyl) prop-1-ene) pyridine derivatives and use thereof | 库尔维斯株式会社 | 2024-09-24 | — | — | CN | claimed |
| US-12234207-B2 | Halo-(3-(phenylsulfonyl)prop-1-enyl)pyridine derivative and use thereof | CUREVERSE INCORPORATED (KR) | 2025-02-25 | — | — | US | disclosed |
| CN-112930345-B | Novel halo- (3- (benzenesulfonyl) prop-1-ene) pyridine derivatives and use thereof | 库尔维斯株式会社 | 2024-09-24 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12234207-B2 | Halo-(3-(phenylsulfonyl)prop-1-enyl)pyridine derivative and use thereof | KEAP1, NFE2L2, NQO1 | USP2 1972/4885PTPN1 2422/4885ABCB1 1335/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.