Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.41 |
| ▸ | CNR1 | P21554 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.36 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.34 |
| ▸ | TSPO | P30536 | 1/20 | 0.34 |
| ▸ | YAP1 | P46937 | 1/20 | 0.34 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.34 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.34 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21723628 | 0.85 | TSHR (0.49) | CNR2CNR1ALDH1A1GRIA2 | |
| SCHEMBL21723900 | 0.85 | PDE2A (0.42) | PYCR1 | |
| SCHEMBL21724804 | 0.82 | DAO (0.43) | ALDH1A1RIPK1TDP1PYCR1BCL2A1 | |
| SCHEMBL21724011 | 0.82 | CNR2 (0.44) | CNR2ALDH1A1 | |
| SCHEMBL21723875 | 0.81 | RIPK1 (0.42) | ALDH1A1GRIA2RIPK1TDP1GRIN2A | |
| SCHEMBL21723579 | 0.76 | RIPK1 (0.42) | RIPK1TSPOPOLB | |
| SCHEMBL21723563 | 0.76 | CETP (0.43) | TDP1 | |
| SCHEMBL21724284 | 0.70 | MEN1 (0.37) | ALDH1A1 | |
| SCHEMBL21724331 | 0.69 | PYCR1 (0.39) | CNR2CNR1ALDH1A1PYCR1TSPO | |
| SCHEMBL21723914 | 0.68 | PYCR1 (0.41) | ALDH1A1TDP1PYCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020035826-A1 | 1,2-DITHIOLONE COMPOUNDS AND USE THEREOF | PI INDUSTRIES LTD. (IN) | 2020-02-20 | — | — | WO | claimed |
| WO-2020035826-A1 | 1,2-DITHIOLONE COMPOUNDS AND USE THEREOF | PI INDUSTRIES LTD. (IN) | 2020-02-20 | — | — | WO | disclosed |