Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 3/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21723974 | 0.81 | CNR2 (0.41) | RIPK1GRIA2GRIN2AALDH1A1TDP1 | |
| SCHEMBL21723579 | 0.80 | RIPK1 (0.42) | RIPK1PGRP2RX7KDM4E | |
| SCHEMBL21723628 | 0.72 | TSHR (0.49) | GRIA2ALDH1A1 | |
| SCHEMBL21724456 | 0.72 | PYCR1 (0.36) | RIPK1MAPK14P2RX7SLC6A2SLC6A4 | |
| SCHEMBL21724487 | 0.70 | RIPK1 (0.33) | RIPK1MAPK14SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL21723900 | 0.70 | PDE2A (0.42) | NR3C1KDM4E | |
| SCHEMBL21723625 | 0.70 | PSEN1 (0.41) | ALDH1A1TAS2R14SLC6A4KDM4E | |
| SCHEMBL21723422 | 0.68 | MAPK14 (0.40) | MAPK14MAOBALDH1A1KDM4E | |
| SCHEMBL21724865 | 0.68 | KDM4E (0.43) | RIPK1ALDH1A1TDP1KDM4E | |
| SCHEMBL21724804 | 0.67 | DAO (0.43) | RIPK1ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020035826-A1 | 1,2-DITHIOLONE COMPOUNDS AND USE THEREOF | PI INDUSTRIES LTD. (IN) | 2020-02-20 | — | — | WO | claimed |