Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4944766 | 0.98 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2MAPTLMNAMEN1 | |
| SCHEMBL31117190 | 0.95 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2MAPTLMNAMEN1 | |
| SCHEMBL20601546 | 0.91 | OPRM1 (0.52) | ALDH1A1SMN1; SMN2MAPTLMNAMEN1 | |
| SCHEMBL3485510 | 0.85 | MAPT (0.53) | ALDH1A1SMN1; SMN2MAPTLMNAOPRM1 | |
| SCHEMBL31368038 | 0.84 | OPRM1 (0.51) | ALDH1A1SMN1; SMN2MAPTLMNAMEN1 | |
| SCHEMBL11047897 | 0.84 | OPRM1 (0.47) | ALDH1A1SMN1; SMN2MAPTLMNAMEN1 | |
| SCHEMBL5639097 | 0.83 | HDAC4 (0.61) | ALDH1A1SMN1; SMN2MAPTLMNAHSD11B1 | |
| SCHEMBL3049424 | 0.83 | HDAC1 (0.51) | ALDH1A1MAPTLMNAOPRM1L3MBTL1 | |
| SCHEMBL8587646 | 0.83 | KDM4E (0.57) | ALDH1A1SMN1; SMN2MAPTLMNAMEN1 | |
| SCHEMBL23163646 | 0.83 | HRH3 (0.47) | ALDH1A1SMN1; SMN2MAPTLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10562878-B2 | Cycloalkylamines as monoamine reuptake inhibitors | SUNOVION PHARAMCEUTICALS INC. (US) | 2020-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10562878-B2 | Cycloalkylamines as monoamine reuptake inhibitors | SLC18A2, SLC6A2, SLC18A3 | ALDH1A1 1474/4885SMN1; SMN2 2392/4885MAPT 969/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.